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Kuniyoshi Shimizu Selected Research

artocarpin lectin

9/2011Artocarpus plants as a potential source of skin whitening agents.
10/2010Cytotoxic effect of artocarpin on T47D cells.
7/2006Inhibitory effect of isoprenoid-substituted flavonoids isolated from Artocarpus heterophyllus on melanin biosynthesis.
1/2002The skin-lightening effects of artocarpin on UVB-induced pigmentation.

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Kuniyoshi Shimizu Research Topics

Disease

13Experimental Melanoma
08/2019 - 07/2006
8Neoplasms (Cancer)
12/2021 - 01/2014
5Prostatic Neoplasms (Prostate Cancer)
10/2010 - 07/2007
4Carcinoma (Carcinomatosis)
10/2021 - 02/2009
3Inflammation (Inflammations)
01/2022 - 01/2017
3Alzheimer Disease (Alzheimer's Disease)
10/2020 - 03/2015
3Hypertension (High Blood Pressure)
08/2018 - 04/2017
3Melanoma (Melanoma, Malignant)
08/2018 - 09/2007
3Hypersensitivity (Allergy)
05/2017 - 07/2013
2Breast Neoplasms (Breast Cancer)
10/2021 - 10/2010
2COVID-19
06/2021 - 08/2020
2Type 2 Diabetes Mellitus (MODY)
08/2020 - 09/2011
2Colorectal Neoplasms (Colorectal Cancer)
10/2018 - 01/2017
2Glaucoma
08/2018 - 04/2017
2Acute Lung Injury
05/2018 - 08/2017
2Obesity
07/2017 - 05/2016
2Acne Vulgaris
07/2017 - 05/2017
2Hyperpigmentation
09/2016 - 01/2002
2Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
02/2009 - 07/2007
1Bites and Stings (Sting)
04/2022
1Pulmonary Fibrosis (Fibrosing Alveolitis)
04/2022
1Fibrosis (Cirrhosis)
04/2022
1Uterine Cervical Neoplasms (Cancer of the Cervix)
02/2022
1Phototoxic Dermatitis (Phototoxicity)
01/2022
1Colitis
01/2022
1Mouth Neoplasms (Oral Cancer)
07/2021
1Squamous Cell Carcinoma of Head and Neck
07/2021
1Ulcerative Colitis
01/2021
1Demyelinating Diseases (Demyelinating Disease)
11/2020
1Hyperglycemia
08/2020
1Lung Injury
08/2020
1Cognitive Dysfunction
01/2020
1Melanosis (Freckles)
07/2019
1Bone Resorption
03/2019
1Dementia (Dementias)
01/2019

Drug/Important Bio-Agent (IBA)

16Melanins (Melanin)IBA
08/2019 - 07/2006
6Pharmaceutical PreparationsIBA
08/2020 - 09/2011
6Monophenol Monooxygenase (Tyrosinase)IBA
08/2012 - 07/2006
5Ethanol (Ethyl Alcohol)IBA
12/2017 - 09/2008
4artocarpin lectinIBA
09/2011 - 01/2002
3TriterpenesIBA
01/2022 - 07/2016
3FlavonoidsIBA
08/2020 - 03/2010
3Biological ProductsIBA
08/2018 - 07/2013
3Hexosaminidases (Hexosaminidase)IBA
05/2017 - 07/2013
3Methanol (Carbinol)IBA
10/2015 - 03/2011
3Bleaching AgentsIBA
08/2012 - 03/2011
3Terpenes (Terpenoids)IBA
09/2011 - 07/2006
3AndrogensIBA
10/2010 - 07/2007
2Proteins (Proteins, Gene)FDA Link
04/2022 - 08/2017
2Adenosine (Adenocard)FDA LinkGeneric
04/2022 - 03/2015
2kaempferolIBA
01/2022 - 03/2015
2Fluorouracil (Carac)FDA LinkGeneric
10/2021 - 10/2018
2Ursolic AcidIBA
11/2020 - 05/2017
2GlucosidasesIBA
08/2020 - 09/2011
2EnzymesIBA
08/2020 - 01/2017
2rho-Associated KinasesIBA
08/2018 - 04/2017
2LipopolysaccharidesIBA
05/2018 - 08/2017
2Matrix Metalloproteinases (MMPs)IBA
02/2018 - 04/2004
2AntigensIBA
04/2017 - 07/2007
2Immunoglobulin E (IgE)IBA
04/2017 - 07/2013
2Indicators and Reagents (Reagents)IBA
07/2016 - 07/2007
2Lipase (Acid Lipase)FDA Link
05/2016 - 07/2013
2LuteolinIBA
03/2015 - 06/2014
2Chlorogenic AcidIBA
03/2015 - 06/2014
2AntioxidantsIBA
07/2013 - 12/2009
2MulberrinIBA
09/2011 - 07/2006
26-prenylapigeninIBA
09/2011 - 07/2006
2PolyphenolsIBA
09/2011 - 09/2007
2cudraflavone CIBA
09/2011 - 07/2006
21,1-diphenyl-2-picrylhydrazylIBA
12/2009 - 10/2009
1dorsomorphinIBA
04/2022
1Bleomycin (Blenoxane)FDA LinkGeneric
04/2022
1heterophyllin BIBA
04/2022
1InterferonsIBA
04/2022
1AMP-Activated Protein KinasesIBA
04/2022
1SteroidsIBA
02/2022
1AcetoneIBA
01/2022
1protocatechuic acidIBA
01/2022
1Catechin (Z 7300)IBA
01/2022
1cucurbitaneIBA
01/2022
1Dextran SulfateIBA
01/2022
1Propolis (Bee Bread)IBA
12/2021
1ricinineIBA
07/2021
1LignansIBA
06/2021
1mogrolIBA
01/2021
1Insulin-Like Growth Factor I (IGF-1)IBA
11/2020
1CuprizoneIBA
11/2020
1AcetylcholinesteraseIBA
10/2020
1Hypoglycemic Agents (Hypoglycemics)IBA
08/2020
1AmylasesFDA Link
08/2020
1Peptide Hydrolases (Proteases)FDA Link
08/2020
1Protein CIBA
08/2020
1ArbutinIBA
08/2019
1hydrocortisone acetate (Cortifoam)FDA LinkGeneric
07/2019
1hydroquinone (Esoterica)FDA Link
07/2019
1Tretinoin (Retinoic Acid)FDA LinkGeneric
07/2019
1MicroRNAs (MicroRNA)IBA
03/2019

Therapy/Procedure

3Therapeutics
07/2018 - 07/2007
1Oral Administration
11/2020
1Home Nursing (Nursing, Home)
01/2020